Abstract:Salmonella typhimurium (S. typhimurium) can cause salmonellosis and is highly drug- resistant, causing seriously hazards on the health of both human and animals. The metabolites of S. typhimurium inoculated on NB medium, dried bean curd and dried beef medium were detected by Gas Chromatography-Mass Spectrometer(GC-MS). Principal component analysis (PCA) and orthogonal partial least squares discrimination analysis(OPLS-DA) were used to identify the characteristic and differential metabolites. The probably metabolic pathways of the characteristic and differential metabolites were analyzed based on the gene annotation of S. typhimurium. Significant growth of S. typhimurium was observed after inoculated dried bean curd and dried beef. The characteristic and differential metabolites were alkanes, phenols, small molecular acids, small molecular alcohols, etc. Gene annotation of S. typhimurium showed a large number of carbohydrate metabolism genes, involved in the production of 1-butanol. Therefore,1-butanol is a typical metabolite of S. typhimurium polluted dried bean curd and beef jerky.
