Rapid Detection of 65 Veterinary Drug Residues in Animal Origin Foods

Abstract:

An analytical method was established for rapid detection of 65 veterinary drug residues in animal origin foods by UHPLC-MS/MS. The samples were extracted with a mixture of acetonitrile and formic acid. The resulting solution was purified by the solid phase extraction column with ProElut PLS-A.The analytes were detected in the multiple reaction monitoring mode.The 65 target compounds showed good linearity（r＞0.99）. The limits of quantification ranged from 0.1 to 1.6 μg/kg. The average recoveries of most veterinary drug residues were in the range of 67. 1%～100.2% and the RSD were less than 7.8%（n=3）. The established method is suitable for rapid detection and analysis of 65 veterinary drug residues in animal origin foods.