Inhibition of Biofilm Formation in Pseudomonas aeruginosa by Cinnamon Extract

Abstract:

The inhibition effect on biofilm production of Pseudomonas aeruginosa PAO1 by the cinnamon extract was studied under the minimum inhibitory concentrations （MIC）. Firstly，it was studied the inhibition effect of the cinnamon extract on the purple pigment production by C. violaceum CVO26 as screening bacteria. Biofilm formation by P. aeruginosa PAO1 was quantitatively determined based on Microplate reader. The profile of the biofilm of PAO1 was observed under light microscope. The results showed that the cinnamon extract under MIC inhibited the purple pigment production of C. violaceum CVO26 and biofilm formation by P. aeruginosa PAO1，and the inhibition rate increased with the increase of the concentration of cinnamon extract. Also，it had obvious influence on the formation of P. aeruginosa PAO1 biofilm profile characteristics. Therefore，the cinnamon extract under MIC had inhibitory effect on the biofilm formation of P. aeruginosa PAO1.