Anti-Prostatic Hyperplasia Activity and Ingredient of Rape Bee Pollen

Abstract:

To research the anti-material of benign prostatic hyperplasia in rape bee pollen，the study is conducted. Ethanol extracts from rape bee-pollen was extracted by different solvent，BPH-induced mouse model is established to study anti-BPH activity. Using a variety of column separation，and the use of 1H-NMR、13C-NMR、135DEPT-NMR to identify the chemical structure. The ethyl acetate extract has significant anti-BPH activity（P<0.05）. Further separation and purification of six compounds were obtained. The use of NMR methods identified as：kaempferol-3-O-β-D- glucopyranoside，octadecatrienoic -9 Z，12 Z，15 Z- trienic acid glycerides，3 '- methoxy-1'-ten eight carbon -9 Z，12 Z，15 Z- three acid glyceride，stearidonic -9 Z，12 Z，15 Z- trienoyl -N- ethyl glycidyl ether，2'-methoxy-1 '，3'-octadecenoic -9 Z，12 Z，15 Z- trienic acid diglyceride，α- linolenic acid.