Effects of Royal Jellies with Different Harvesting Time

Abstract:

This study aimed to explore effects of royal jellies having different harvesting time on the immunity of mice. Results showed that no significant effects（P>0.05） on the ratios of organ/body weight of Balb/c mice were observed with three doses（9 000，3 000 and 1 000 mg/kg） of 48 h or 72 h royal jellies. In the delayed type hypersensitivity experiment，feeding the highest dose of 48 h or three doses of 72 h royal jellies daily by oral gavage for 30 days to mice induced by dinitrofluorobenzene resulted in remarkable effects（P <0.05） on the weight differences of ear slices. For the carbon clearance ability experiment，the clearance index and phagocytic index of mice fed with the highest dose of 48 h，the medium or highest doses of 72 h royal jellies daily by oral gavage for 45 days and then injected with ink from the eye canthi were statistically significant（P<0.05） compared to those of the control group. Therefore，both 48 h and 72 h royal jellies could enhance the immunity of mice with the latter being superior to the former.