Effects of Longan Seed on Learning and Memory Ability in Dysmnesia Mice

Abstract:

In the aquired dysmnesia and reproduction memory disorders models caused by scopolamine and alcohol respectively，maze test and step-through test were used to observe and compare the effects of longan seed and piracetam on learning and memory ability in dysmnesia mice. The results showed that the extract of longan seed can obviously improve the learning and memory ability. As compared with model group，extract of longan seed at the dose of 1.2 g?kg-1 and 2.4 g?kg-1 could prolong the latent period（P<0.05），reduce error hits（P<0.05） and shorten reaction time（P<0.05）. There was no significant difference between the longan seed and piracetam （P＞0.05）. In summary，the longan seed can obviously improve the learning and memory ability in dysmnesia mice ，and the mechanism of improvement can be studied in further research.