Effect of Phosphodiesterase Inhibitors on Adenosine-3',5'-Cyclic Monophosphate Production by Fermentation with Bacillus. subtilis

doi:10.3969/j.issn.1673-1689.2014.08.008

Home > Archive>Volume 33, Issue 8, 2014 >837-840. DOI:10.3969/j.issn.1673-1689.2014.08.008

Effect of Phosphodiesterase Inhibitors on Adenosine-3',5'-Cyclic Monophosphate Production by Fermentation with Bacillus. subtilis
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                        10.3969/j.issn.1673-1689.2014.08.008
                    
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In order to improve the accumulation of Adenosine-3', 5'-cyclic monophosphate with Bacillus. subtilis jsim-1277, the effects of phosphodiesterase inhibitors were studied. The results showed that Cemadotin and Aminophylline can improve the concentration of Adenosine-3', 5'-cyclic monophosphate. Under the optimized conditions, the productivity increased 28%, reaching 9.14 g/L.

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ZHU Xiaohong, ZHU Xiaohui, WEI Wei. Effect of Phosphodiesterase Inhibitors on Adenosine-3',5'-Cyclic Monophosphate Production by Fermentation with Bacillus. subtilis[J]. Journal of Food Science and Biotechnology,2014,33(8):837-840.

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Online: October 19,2014
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