Abstract:In this paper, the best technology of extraction polyphenols from raspberry was discussed. A high-speed shear dispersing emulsifier(HSDE) was used to treat raspberry. The effects of the acetone concentration, HSDE rotary speed, treatment time were investigated. A predictive polynomial quadratic model was set up by means of central composite design and used to optimize these treatment conditions by response surface methodology. The optimal HSDE treatment conditions were determined as 85% of the acetone concentration, 18 000 r/min of HSDE rotary speed, 186s of treatment time. After optimization polyphenol content of raspberries were 710.69 mg/hg fresh weights. The contents of flavonols and anthocyanin were 219.997 mg/hg and 26.751 mg/hg fresh weights. Compared to conventional ultrasonic wave assisted extraction for polyphenol from raspberries greatly saved extraction time and avoided the loss and degeneration of the active principle. In conclusion, HSDE treatment is a good pretreatment strategy that can provide a high disruption rate in a short time.