Aptamer and Related Progress

Abstract:

Aptamers are single-stranded oligonucleotides with the high affinity and high specificity binding of the target molecules. They can be obtained by systematic evolution of ligands by exponential enrichment(SELEX) in vitro screening. Aptamer is similar but superior to antibody,and it is becoming one specific issue of detection nowadays. This manuscript reviews the aptamer,screening methods,as well as applications in the analysis,food safety,clinical care and other areas in recent years.