Abstract:The aim of this manuscript was to investigate the effects of taurine on iron utilization and antioxidative ability of iron deficiency anemia(IDA) rats and normal rats,for those,the iron utilization and antioxidative ability in IDA rats and normal rats were determined after gavaged 0.5 g/kg taurine for 21 days.The IDA rat model was established through fed iron deficiency feed to the SD rats Hemoglobin,serum iron,serum ferritin,total iron binding capacity and the content of liver and spleen iron,MDA,SOD,GSH-Px and T-AOC were determined respectively after the end of the intervention.It was found that the addition of taurine in IDA rats increased hemoglobin,serum iron,serum ferritin,the content of liver iron and decreased the total iron binding capacity significantly(P < 0.05).Adding taurine improved the antioxidative ability in IDA rats,especially when adding iron in the same time.Adding taurine had no significant effects on iron utilization and antioxidative ability in normal rats(P > 0.05).Therefore,the effects of taurine on iron utilization and antioxidative ability in the IDA rats were better than that of the normal rats.
