Abstract:In this study,air dried asparagus was ultrasonic extracted with 75 %(v/v)ethanol.The immune function of this extract on mice were investigated.Mice were orally administrated with asparagus extract at three dose levels(7,70,140 mg/Kg BW) for 30 days.At the organ level,thymus and spleen were weighed and their indices were calculated.The macrophage phagocytosis ability in vitro,transformation of spleen lyphmocytes,and serum hemolysin were investigated to assess the immune functions.The results showed that the middle and high dosage of asparagus extract promoted the spleen index and the phagocytic function of murine peritoneal macrophages.the middle and high dosage of asparagus extract significantly enhanced the transformation of spleen lyphmocytes and serum hemolysin(HC50).This suggest that asparagus extract can enhance both the specific and non-specific immune functions in normal mice.Moreover,the specific immune effects of asparagus extract especially depended on the dosage.
