Study on the Properties of Complex Films Based on Chitosan and Sodium Cellulose Sulfate

Abstract:

In order to assess the potential of polyelectrolyte complex films composed of chitosan and sodium cellulose sulfate(NaCS) for controlled drug release,effects of chitosan Mw,Mw and substitution degree of NaCS on the mechanical(strength and brittleness) and swelling properties of the complex film were studied.The results showed that chitosan Mw,and the Mw and substitution degree of NaCS have great influence on the mechanical and swelling properties of chitosan/NaCS films.Higher elongation at break of the complex films would be obtained with chitosan of higher Mw.Meanwhile,the increase of the Mw and substitution degree of NaCS would cause the decrease of the swelling ratios.In addition,pH of the solution has great influence on the swelling ratios of chitosan/NaCS films.