Effect of Pomegranate Peel Polyphenols on Lipid Peroxidation in Vitro

Abstract:

The purpose of this manuscript is to study the inhibitory effect of the pomegranate peel polyphenols on the peoxidation of poly unsaturated fatty acid and to identify the key composition.For this,three classical anti-lipid peroxidation model,namely yolk system,low density lipoprotein system and rat liver homogenate system were used to investigate the effect of the purified pomegranate peel polyphenols(PPPs),Punicalagin and ellagic acid(EA)on the antioxidant activity.Results showed that PPPs exhibited a good protection against metal ions-induced lipid peroxidation in vitro in a dose-depend s.In addition,the trend in anti-lipid peroxidation activity was Punicalagin>EA>PPPs,from this we can concluded that Punicalagin the key anti-lipid peroxidation component in pomegranate peel polyphenol mixtures.