Prediction of the Structure and Antigenic Epitopes of Cashew Allergen Ana o 2

Abstract:

Cashew is one of the foods which can cause people allergic.In this manuscript,the sequence characteristics,secondary and tertiary structure,antigenic epitopes,hydrophobicities and surface accessibility,flexibility of allergen Ana o 2 from cashew were predicted and analyzed by using bioinformatics methods,such as Pubmed,SOPMA,swiss-model and DNAStar.Results demonstrated that the epitopes of Ana o 2 are probably at 108-111,181-186,217-218,234-238,244-255,283-287.These should be helpful for the further research of cashew allergen and be useful to develop of low sensitization cashew products.