Preparation of HP-β-CD & Rose Flavor Nanocapsulates

Abstract:

Hydroxypropyl-β-cyclodextrin(HP-β-CD),containing special hydrophobic cavity,was used to include rose flavor.In this study,the average size was as major index and PDI and ζ potentia as t two auxiliary indexes to choose the optimum process parameters.The optimum conditions were determined by single-factor and he Box-Behnken design of response surface methodology and listed as follows: reaction time of 4h,electromagnetic stirring speed of 1000rpm,reaction pH of 8,the mass ratio of external to internal capsule of 1.69,the emulsifier of Tween-20,the mass ratio of emulsifier to flavor of 3.13,solid contents of 1.5%.under the optimum conditions,the average size is 72.8nm,the PDI is 0.127,and the ζ potential is-12.6mv.It also has a spherical shape by the transmission electron microscopy.