Study of the Prevention and Treatment Action of VC on Histamine Toxicity in Mice

Abstract:

To discuss the toxicity induced by histamine on mice and the protective effects of Vitamin C(VC).the results demonstrated that histamine had no effect on drinking water and diet in mice,but it decreased pain threshold and autonomic activity in mice.The index of organ of kidney,stomach,intestinal,thymus and the activities of SOD were reduced by histamine,MDA were increased.VC had a preventive action on pain threshold and the index of organ.VC also had significant effect on SOD activity and autonomous activity.