Synthesis of O-benzoyl-Chitosan and Its Antifungi Activity

Abstract:

This study ssing MeSO3H as catalyst and protecting agent to synthesizeO-benzoyl-chitsan by esterification between chitosan and benzoyl chloride.The structure of the product was analyzed by FITR and 1H-NMR spectroscopy.The esterification mainly occurred on OH group rather than-NH2 group of chitosan.The average degree of substitution(DS) was 0.35.The anti-fungi activity of O-benzoyl-chitsan against the grey mould,Botrytis cinerea was carried out.The result showed that the EC50 of chitosan and O-benzoyl-chitosan were 1.55 mg mL-1 and 0.27 mg mL-1,respectively.The anti-fungi activity of O-benzoyl-chitosan was much stronger than that of chitosan.