Study on the Mechanism of Tartary Buckwheat Protein on Breast Cancer Cells

Abstract:

The mechanism of tartary buckwheat protein on breast cancer cells was studied by Flow cytometry(FCM).The inhibition effect of TBWSP31 on the proliferation of Bcap37 cell existed in dose-and time-dependent manners.After treatment with TBWSP31,Bcap37 cell resulted in the accumulation of the cell in G0/G1,and prevented the cell growing from G0/G1 phase to S phase.The cell cycle was related to G1 phase,and the longer G1 phase could slow the speed of cell malignant proliferation.The expression of bcl-2 and Fas were detected quantitatively by FCM.Based on the above results,it can be concluded that the antitumor mechanism was associated with the increasing expression of Fas and the decreasingd expression of bcl-2.