Measurement Uncertainty in the Determination of Benzoic Acid in Reconstituted Tobacco Sheet with HPLC

Abstract:

This manuscript study the measurement uncertainty during the determination of benzoic acid in the reconstituted tobacco sheets by high performance liquid chromatography(HPLC).For this,a mathematic model was established and the source of the uncertainty was analyzed.Each components of uncertainty was estimated by analyzing the various variable parameters among the procedures,the combined uncertainty was then finally determined by synthesizing the uncertainties of various component variables.The results showed the mathematic model was reasonable and reliable.