A Review of Tyrosine Ammonia Lyase in Microorganism

Abstract:

Production of secondary metabolities by microbial transformation is a very effective means.However,no C4H and coumaric acid are found in microorganism,this limited the large scale of production of secondary metabolities from phenylalanine metabolism pathway.L-tyrosine was catalysised to form p-coumaric acid by tyrosine ammoni lyase without C4H,Base on the advantage,zymologic feature crystal structure,catalytic mechanism and genetic engineering of TAL were reviewed in this manuscript.