益生菌对糖脂代谢紊乱相关疾病的缓解作用及机制

Alleviating Effect and Mechanism of Probiotics on Glycolipid Metabolism Disorder

摘要:

糖脂代谢紊乱是常见内源性疾病发病的重要因素，其相关疾病的发病率逐年上升，严重影响患者的生活质量。益生菌是对人体健康有益的微生物，可通过调节肠道微生物起到降低血糖、调节血脂、改善氧化应激及炎症的作用。作者综述了益生菌在高脂血症、糖尿病、高血压这3种糖脂代谢紊乱相关疾病中的具体作用效果及其相关机制。作为一种非药物性降糖、降脂方法，益生菌为糖脂代谢紊乱相关疾病的干预治疗提供了新思路。

Abstract:

Disorder of glucose and lipid metabolism is an important factor contributing to the prevalence of common endogenous diseases, and the incidence of related diseases is increasing annually, severely impacting the quality of life of individuals. Probiotics, widely applied in daily foods as microorganisms beneficial to human health, can reduce blood glucose, regulate blood lipids, and improve the level of oxidative stress and inflammation by adjusting intestinal microbes. The author reviews the specific efficacy and relevant mechanisms of probiotics in three glucose-lipid metabolism disorder-related diseases, i.e., hyperlipidemia, diabetes, and hypertension. As a non-drug therapy for reducing blood sugar and lipids, probiotic provides a new prospect for the intervention and treatment of diseases related to glucose and lipid metabolism disorders.