Abstract:There are a large number of inorganic ions in D--ribose fermentation broth, which will affect the subsequent purification of D--ribose if not removed. At present, ion exchange resins are often adopted for desalination in industry. The cost of desalination increases proportionally with the increase of feed liquid salt content, and generates a large amount of wastewater, which is neither economical nor environmentally friendly. In order to determine the feasibility of electrodialysis desalination, the specific cost of desalination and the best desalination process, the desalting experiment of electrodialysis was carried out with the filtrate of D--ribose fermentation broth as the raw material and Lanran-40-2040 composed of homogeneous cation exchange membrane CMX and anion exchange membrane AMX as the laboratory-scale equipment. The results showed that when the desalination rate was controlled at 54%, the product yield reached 97.68%. However, when the desalination rate was further increased, a certain amount of D--ribose would permeate into the electrodialysis concentration chamber, and the D--ribose content in the concentration chamber increased rapidly with the increase of operation time. Compared with the whole resin desalination process, the product yield of electrodialysis combined with ion exchange resin desalination process was increased by 1.9%, which saved half of the ion exchange resin, acid and alkali, and reduced half of the wastewater discharge. Therefore, this study could provide a good reference for the industrial production ofD--ribose.