硫酸多糖生物活性研究进展

Research Progress on Bioactivity of Sulfate Polysaccharide

摘要:

硫酸多糖也被称为多糖的硫酸化衍生物，是硫酸根取代了多糖结构中单糖分子的部分羟基而形成的一类具有多种功能的物质，可以通过天然提取或硫酸化的结构修饰而得到。近年的研究证明硫酸多糖具有显著的抗肿瘤、抗病毒、抗氧化、抗凝血等活性，对机体免疫系统有一定调控作用。作者对硫酸多糖生物学功能的近期研究进行了总结，并对后续研究进行了展望。

Abstract:

Sulfated polysaccharides can be extracted from natural resources or modified from polysaccharides through substitution of the hydroxyl groups of monosaccharide molecules on polysaccharide chains by sulfate. The sulfated polysaccharides have multiple functions，such as anti-tumor，anti-virus，anti-oxidation，anti-coagulation and immunoregulation. In this paper，the recent studies on the biological functions of sulfated polysaccharides were summarized，and the future research was proposed.