Application of Candida antarctica Lipases in the Preparation of Diacylglycerol

Abstract:

Candida antarctica (C. antarctica) is a yeast species found in the Antarctic environment. It produces two lipases, C. antarctica lipase A (CALA) and C. antarctica lipase B (CALB). In recent years, C. antarctica lipases have been widely used in the biological, chemical, and food industries for their strong catalytic efficiency and unique positional selectivity. This review first introduces the structural and enzymatic characteristics of C. antarctica lipases and then describes the application status of C. antarctica lipases in the preparation of diacylglycerol (DAG). Finally, the biological modification and immobilization status of the lipases are concluded and prospected. This review aims to provide theoretical and technical reference for the research on C. antarctica lipases in the fields such as DAG hydrolysis and esterification preparation and lay a foundation for the subsequent transformation and improvement of enzyme molecules.