Research Progress in Aptamer Sensors for the Detection of Ochratoxin A

Abstract:

Ochratoxin A (OTA) is a mycotoxin ubiquitous in food crops, fruits, and animals. It is one of the most toxic substances, exerting teratogenic and cytotoxic effects on the human body. An aptamer is an oligonucleotide sequence obtained by screening in vitro. Since aptamers have high affinity and strong specificity to corresponding ligands, aptamer sensors can be constructed to detect OTA. These aptamer sensors have high sensitivity, strong affinity, and good stability. The author reviews the research progress in four aptamer sensors for OTA detection, summarizes the OTA detection methods of current aptamer sensors, and proposes the future research directions of aptamer sensors, which is of great significance for the trace and sensitive OTA detection.