Research Progress in Effects of Bile Acids and Their Receptors on Intestinal Function

Abstract:

Bile acids are the main end products of cholesterol metabolism in the body, playing an important regulatory role in the digestion and metabolism of nutrients, especially lipids. The intestine is the main organ for digestion and absorption, as well as an important site for bile acids to achieve liver-intestinal circulation. Its function is closely related to the interaction between bile acids as signaling molecules and their receptors. Focusing on the metabolism and regulatory mechanism of bile acids, the author reviews the roles and underlying mechanisms of bile acids and their receptors in regulating intestinal barriers, immune function, and gut microbiota. The aim is to provide reference for related research on improving intestinal health by bile acids and their receptors.