Research Progress on Tropomyosin Allergen in Aquatic Animals

Abstract:

Tropomyosin(TM) is a common pan-allergen in crustaceans, and its allergenicity is also confirmed in certain kinds of fish. Tropomyosin has a conservative structure, high homology, strong allergenicity and extensive immune cross-reactivity. The studies of tropomyosin allergenicity and its reduction method, immune cross-reaction are all related to the epitope on tropomyosin. Accordingly, epitope is the key target of tropomyosin research. This article briefly reviews the recent progress in aquatic tropomyosin study, including the properties, epitopes, immune cross-reactivity, allergenicity and its reduction.