Study on Antimicrobial Activities of Polysaccharides from Artemisia argyi and Its Stability

Abstract:

Artemisia argyi polysaccharide extracted by hot water and measurement the antibacterial activity and minimum inhibitory concentration（MIC） of polysaccharides by using the filter paper method，also studied the pH stability，thermal stability，UV stabilizers stability of Artemisia polysaccharide antibacterial activity. The results showed that：Artemisia argyi polysaccharides have a certain inhibitory effect on three common bacteria，and have strong effect on gram-positive bacteria Staphylococcus aureus and Bacillus subtilis，but the effect on gram-negative bacteria E. coli is weak.The MICs of the polysaccharide agaginst Bacillus subtilis，Staphylococcus aureus and Escherichia coli were 0.625、0.625、1.25 mg/mL respectively. The antimicrobial activities of the polysaccharide were stable under the conditions of heat and ultraviolet ray，but were unstable under different pH values，strong in acid and weak in base. Artemisia argyi polysaccharide has good antibacterial activity，it can be used for the development and utilization of natural food preservatives.