Antibacterial Study of Silver Nanoparticles Biosynthesized with Ginger Extract

Abstract:

Ginger（Zingiber officinale Roscoe） extract was found to have a brand new application in this paper. The antibacterial silver nanoparticles（AgNPs） were synthesized using ginger extract as a reducing agent，which avoid the disadvantages of environmental hazards in traditional methods. The as-prepared AgNPs were fully characterized by means of UV-visible（UV-vis） spectroscopy，transmission electron microscopy（TEM） and X-ray diffraction（XRD） technique. The results showed that the AgNPs was face-centered cubic structure，and the spherical-shaped nanoparticles were polydisperse in the size range 5~30 nm. The synthesized silver nanomaterials showed remarkable antibacterial activity against all tested pathogens including four kinds of multidrug resistant clinical isolates and four kinds of aquatic pathogens. The minimum inhibitory concentration（MIC） and the minimum bactericidal concentration（MBC） of the AgNPs against Staphylococcus aureus were 25.7 μg/mL and 51.4 μg/mL，respectively. Moreover，stability studies showed that the biosynthesized AgNPs had excellent long-term stability as well as thermal stability. Therefore，the ginger extract could be used to synthesize a new kind of AgNPs with stable and broad-spectrum antimicrobial activity.