Progress on Microbial Fermentation Production of L-Leucine

Abstract:

Microbial fermentation was the mainly method to product L-leucine presently. Improving the strain production of L-leucine by breeding high-yielding strains is helpful for shortening of the gap with foreign production and improving our international competitiveness with foreign. This paper stated the methods of L-leucine production,regulation of biosynthesis enzymes,transporter and leucine responsive protein,and the research evolution of the breeding of L-leucine hyper-producter were summarized at home and abroad.