Protective Effects and Mechanism of Ganoderma Lucidum Triterpenoids on Learning and Memory Function of Alzheimer Disease Model Animals

Abstract:

In order to elucidate the protective effects and mechanism of Ganoderma Lucidum Triterpenoids(GLT) on Alzheimer Disease model animals,two different groups rats was divided.it was found that the model animals exhibited the worse ability in learning and memory and a lower Na+-K+-ATPase activity.The addition of GLT significantly improved the above indexes(P<0.05).GLT can protect AD model animals,GLT improved the learning and memory dysfunction in aging model rats,the following mechanism may be improving energy metabolism in brain.