Research on the Connection Bias of Amino Acids Based on Probability Transition Matrix

Abstract:

In this manuscript,a novel concept of lumping map and a computing method of the transition probability in lumped process were suggested based on Markov model,to investigate the connection bias of amino acids.The results demonstrated that the connection of amino acids had a particular preference which was related to the classification of amino acids,and further verified the scientific of the classification of amino acids.At the same time,the preference would give some help for the prediction of amino acids sequence.