Anti-Inflammatory Activities of Water Extract from Honeycomb

Abstract:

The aim of this study is to explore the pharmacological activities of honeycomb against acute inflammation in animals,for this,the effect of water extracts from Apis cerana cerana honeycomb and A.mellifera ligustica honeycomb on Xylene-induced ear edema,acetic acid-induced vascular permeability and carrageenan-induced hind paw edema tests in mice were investigated.The results showed that both samples exhibited remarkable inhibition in xylene-induced ear edema model,carrageenan-induced hind paw edema model and the content of PGE2 in the inflammatory tissues,while they showed no anti-inflammatory against acetic acid-induced vascular permeability.The pharmacological activities of the water extracts of A.cerana cerana honeycomb show in a concentration-dependent manner.