The Radical Scavenging Effect of N-Acyl Chitosan Oligosaccharide

Abstract:

N-maleyl chitosan oligosaccharide (NMCOS) and N-phthaloyl chitosan oligosaccharide (NPCOS) with the same substituting degrees (0.25) were synthesized.The structure were characterized by FTIR spectra,the molecular weight was measured by Gel Permeation Chromatog-raphy (GPC).Their antioxidant activity were evaluated by the scavenging of hydroxyl radical (.OH) and 1,1-Diphenyl-2-picrylhydrazyl radical ( DPPH).The results showed NPCOS have stronger hydroxyl and DPPH radical scavenging activity than that of NMCOS.The results presented here demonstrated that the antioxidant activity of N-acyl Chitosan Oligosaccharide with the same substituting degrees was determined by the substituting groups.