乳酸菌的抗氧化活性机制及其在氧化应激相关疾病中的应用

Mechanisms of Antioxidant Activity of Lactic Acid Bacteria and Its Application in Oxidative Stress-related Diseases

摘要:

乳酸菌的抗氧化特性与其多种益生活性有关，可以预防和缓解宿主体内氧化引起的多种慢性疾病。作者详细阐述了乳酸菌抗氧化的作用机制，包括抗氧化酶类和非酶促抗氧化物质的作用机理、调控宿主的抗氧化信号通路，总结了乳酸菌的抗氧化特性在神经系统、消化系统和皮肤系统疾病方面的应用现状，旨在探索如何在氧化应激相关疾病中增强乳酸菌的抗氧化活性，以期为相关治疗策略提供新思路。

Abstract:

The antioxidant properties of lactic acid bacteria are related to various probiotic activities, which can prevent and alleviate a variety of chronic diseases caused by oxidation in the host. The antioxidant mechanisms of lactic acid bacteria, including the action mechanisms of antioxidant enzymes and non-enzymatic antioxidants and regulation of host signaling pathways, were expounded. Furthermore, the application status of antioxidant properties of lactic acid bacteria in diseases of the nervous system, digestive system, and skin system were summarized. The aim is to explore how to enhance the antioxidant activity of lactic acid bacteria in oxidative stress-related diseases and give new insights into the development of related treatment strategies.