猴头菇β-葡聚糖促进人肠道菌群产丁酸的研究进展

Research Progress on β-Glucan from Hericium erinaceus Promoting Butyric Acid Produced by Human Intestinal Flora

摘要:

丁酸是结肠上皮细胞首选能量来源, 可提高肠屏障的完整性, 促进人的肠道健康。已有关于猴头菇β-葡聚糖(HEBG)促进人肠道菌群产丁酸的作用的报道，但有关其调控机制还不清楚。作者介绍了HEBG的制备方法及获得的具有不同结构特征的HEBG，并对人粪便中产丁酸特性的菌群进行了总结，最后综述了不同来源β-葡聚糖调控肠道菌群产丁酸的机制及研究进展。猴头菇β-葡聚糖是一种优良的膳食纤维，它可能通过直接或间接模式促进人肠道菌群产丁酸。本综述对猴头菇β-葡聚糖益生功能的开发及健康食品的创制具有指导性意义。

Abstract:

Butyric acid is the preferred energy source for colon epithelial cells, which improves the integrity of the intestinal barrier and promotes human intestinal health. It has been reported that Hericium erinaceus β -glucan (HEBG) promotes the production of butyric acid by human intestinal flora, but the regulatory mechanism remains unclear. In this paper, the preparation methods of HEBG and the obtained HEBG with different structural characteristics were reviewed. Then, this paper summarized the bacteria with the characteristic of producing butyric acid in human feces, and reviewed the research progress of the mechanism of β-glucan regulating the intestinal bacteria producing butyric acid from different sources. It is concluded that Hericium erinaceus β-glucan is an excellent dietary fiber, which may promote the production of butyric acid by human intestinal flora through direct or indirect mode. This review has guiding significance for the development of the probiotics of β-glucan and the creation of healthy food of Hericium erinaceus.